Development of layer-specific axonal arborizations in mouse primary somatosensory cortex
نویسندگان
چکیده
منابع مشابه
Development of layer-specific axonal arborizations in mouse primary somatosensory cortex.
In the developing neocortex, pyramidal neurons use molecular cues to form axonal arbors selectively in the correct layers. Despite the utility of mice for molecular and genetic studies, little work has been done on the development of layer-specific axonal arborizations of pyramidal neurons in mice. We intracellularly labeled and reconstructed the axons of layer 2/3 and layer 5 pyramidal neurons...
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Although each subdivision of primary somatosensory cortex (SI) receives dense input from the thalamus, but the exact location and type of information that the fibers convey have not been identified yet. In the present study, the exact source of thalamocortical fibers to areas 2 and 3b was investigated using tract-tracing techniques. Following injection of tracer into area 3b, labeled neurons ...
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An in vitro brain slice preparation has been used to label fibers connecting the somatosensory thalamus and cortex of the mouse. In 400-800-micron brain slices, the pathway between the ventrobasal complex and somatosensory cortex was labeled under direct vision with horseradish peroxidase crystals (HRP), HRP-Nonidet P-40 (NP40) detergent chips, or a solution of HRP/dimethylsulfoxide. Thalamocor...
متن کاملLong-term, layer-specific modification of spontaneous activity in the mouse somatosensory cortex following sensory stimulation
20 pages, 6 figures. CC-BY 4.0 International license not peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was. 2. CC-BY 4.0 International license not peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was. 3 Neocortical circuits exhibit spontaneous neuronal activity whose ...
متن کاملPOm Thalamocortical Input Drives Layer-Specific Microcircuits in Somatosensory Cortex.
Higher-order thalamic nuclei, such as the posterior medial nucleus (POm) in the somatosensory system or the pulvinar in the visual system, densely innervate the cortex and can influence perception and plasticity. To systematically evaluate how higher-order thalamic nuclei can drive cortical circuits, we investigated cell-type selective responses to POm stimulation in mouse primary somatosensory...
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ژورنال
عنوان ژورنال: The Journal of Comparative Neurology
سال: 2005
ISSN: 0021-9967,1096-9861
DOI: 10.1002/cne.20754